PGC-1α sparks the fire of neuroprotection against neurodegenerative disorders
Abstract
Recently, growing evidence has demonstrated that peroxisome proliferator activated receptor γ (PPARγ) coactivator-1α (PGC-1α) is a superior transcriptional regulator that acts via controlling the expression of anti-oxidant enzymes and uncoupling proteins and inducing mitochondrial biogenesis, which plays a beneficial part in the central nervous system (CNS). Given the significance of PGC-1α, we summarize the current literature on the molecular...
Paper Details
Title
PGC-1α sparks the fire of neuroprotection against neurodegenerative disorders
Published Date
Jul 1, 2018
Journal
Volume
44
Pages
8 - 21
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