Spontaneous fertility in a male patient with testotoxicosis despite suppression of FSH levels
Abstract
Testotoxicosis is a rare cause of peripheral precocious puberty in boys caused by constitutively activating mutations of the LHCG receptor. Affected males usually have normal gonadotropin profiles and fertility in their adult life. Here, we described the long-term follow-up of a 24-year-old young man with severe testotoxicosis due to a de novo activating mutation in the third transmembrane helix of the LHCGR (p.Leu457Arg). This patient was...
Paper Details
Title
Spontaneous fertility in a male patient with testotoxicosis despite suppression of FSH levels
Published Date
Mar 12, 2018
Journal
Volume
33
Issue
5
Pages
914 - 918
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