Myeloid derived-suppressor cells: their role in cancer and obesity
Abstract
Myeloid-derived suppressor cells (MDSC) are present in most individuals with cancer where they inhibit adaptive and innate antitumor immunity and are an obstacle to cancer immunotherapies. Chronic inflammation is characteristic of adipose tissue and is a risk factor for the onset and progression of cancer in obese individuals. Because MDSC accumulate in response to inflammation, it has been hypothesized that one of the mechanisms by which...
Paper Details
Title
Myeloid derived-suppressor cells: their role in cancer and obesity
Published Date
Apr 1, 2018
Volume
51
Pages
68 - 75
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