Cellular senescence: Immunosurveillance and future immunotherapy
Abstract
In response to persistent DNA damage, induction into cell senescence promotes an immunogenic program which facilitates immune clearance of these damaged cells. Under physiological conditions, senescent cells can activate both innate and adaptive immune responses, functioning to maintain tissue homeostasis. In addition, emerging findings suggest that programmed induction of cell senescence may be important for regulating reproductive processes,...
Paper Details
Title
Cellular senescence: Immunosurveillance and future immunotherapy
Published Date
May 1, 2018
Journal
Volume
43
Pages
17 - 25
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Notes
History