Alterations in the Rho pathway contribute to Epstein-Barr virus–induced lymphomagenesis in immunosuppressed environments
Abstract
Key Points EBV-induced DLBLs are characterized by genomic and transcriptomic alterations in the Rho pathway. Targeting the Rho pathway using a ROCK inhibitor, fasudil, inhibited tumor growth in EBV-positive DLBL patient-derived xenograft...
Paper Details
Title
Alterations in the Rho pathway contribute to Epstein-Barr virus–induced lymphomagenesis in immunosuppressed environments
Published Date
Apr 26, 2018
Journal
Volume
131
Issue
17
Pages
1931 - 1941
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Notes
History