A role for KCC3 in maintaining cell volume of peripheral nerve fibers
Abstract
The potassium chloride cotransporter, KCC3, is an electroneutral cotransporter expressed in the peripheral and central nervous system. KCC3 is responsible for the efflux of K+ and Cl− in neurons to help maintain cell volume and intracellular chloride levels. A loss-of-function (LOF) of KCC3 causes Hereditary Motor Sensory Neuropathy with Agenesis of the Corpus Callosum (HMSN/ACC) in a population of individuals in the Charlevoix/Lac-Saint-Jean...
Paper Details
Title
A role for KCC3 in maintaining cell volume of peripheral nerve fibers
Published Date
Feb 1, 2019
Journal
Volume
123
Pages
114 - 124
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