Total syntheses and endoplasmic reticulum stress suppressive activities of hericenes A−C and their derivatives
Abstract
We report the syntheses and neuroprotective activities of hericenes and their derivatives against endoplasmic reticulum (ER) stress-dependent cell death. Four natural products, including hericenes A−C and hericenol A, and five synthetic derivatives were synthesized and their protective activities were evaluated. In designing the synthetic derivatives, we focused on the binding position of the fatty chain. Hericenes B and C showed moderate...
Paper Details
Title
Total syntheses and endoplasmic reticulum stress suppressive activities of hericenes A−C and their derivatives
Published Date
May 1, 2018
Journal
Volume
59
Issue
18
Pages
1733 - 1736
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