Formation of osteon‐like structures in unidirectional porous hydroxyapatite substitute

Unidirectional porous hydroxyapatite (UDPHAp) bone substitute comprises a microstructure of cross‐sectionally oval pores with diameters ranging from 30 to 300 µm. Bone remodeling within the UDPHAp is expected upon implantation into bone; however, the mechanism and factors influencing this bone growth remain unclear. The objectives of the present study were to assess the vasculature and microstructure of newly formed bone and to determine how...