Ghrelin potentiates cardiac reactivity to stress by modulating sympathetic control and beta-adrenergic response

Prior evidence indicates that ghrelin is involved in the integration of cardiovascular functions and behavioral responses. Ghrelin actions are mediated by the growth hormone secretagogue receptor subtype 1a (GHS-R1a), which is expressed in peripheral tissues and central areas involved in the control of cardiovascular responses to stress.In the present study, we assessed the role of ghrelin - GHS-R1a axis in the cardiovascular reactivity to acute...