Nonlinear pattern of the emergence of white matter hyperintensity in healthy Han Chinese: an adult lifespan study

White matter hyperintensities (WMHs) are prevalent in the older adult and are often accompanied by cognitive decline and an increased risk of dementia. However, the roles of WMHs in the periventricular white matter and deep white matter regions in the aging process remain controversial. This study aimed to investigate the WMH burden across the adult lifespan and determine the interrelationships among age, WMH, and cognition. The present study...