Turmeric (Curcuma longa) and its major constituent (curcumin) as nontoxic and safe substances: Review

Curcumin is the major constituent of turmeric ( Curcuma longa ). Turmeric has been widely used as a spice in foods and for therapeutic applications such as anti‐inflammatory, antihyperlipidemic, and antimicrobial activities. Turmeric and curcumin are nonmutagenic and nongenotoxic. Oral use of turmeric and curcumin did not have reproductive toxicity in animals at certain doses. Studies on human did not show toxic effects, and curcumin was safe at...