Loganic Acid Methyltransferase: Insights into the Specificity of Methylation on an Iridoid Glycoside

Volume: 19, Issue: 8, Pages: 784 - 788
Published: Mar 8, 2018
Abstract
Loganin is an iridoid glycoside of interest as both an intermediate in the biosynthesis of indole alkaloids in plants and as a bioactive compound itself. Loganic acid methyltransferase catalyzes the methylation of a monoterpenoid glycoside precursor to produce loganin and demonstrates stereospecificity for the (6S,7R) substrate. We have biochemically characterized this biocatalyst and elucidated the basis for its strict substrate specificity....
Paper Details
Title
Loganic Acid Methyltransferase: Insights into the Specificity of Methylation on an Iridoid Glycoside
Published Date
Mar 8, 2018
Volume
19
Issue
8
Pages
784 - 788
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