Regulation of angiopoietin-like 4 and lipoprotein lipase in human adipose tissue

•ANGPTL4 mRNA is highest in the subcutaneous adipose tissue of obese individuals. •ANGPTL4 and LPL mRNA levels positively associate in multiple adipose tissue depots. •ANGPTL4 and LPL protein levels negatively associate in subcutaneous adipose tissue. •Adipose tissue ANGPTL4 mRNA levels are higher in the fasted than the postprandial state. Background Elevated plasma triglycerides are increasingly viewed as a causal risk factor for coronary...