Genotype imputation performance of three reference panels using African ancestry individuals.
Abstract
Genotype imputation estimates unobserved genotypes from genome-wide makers, to increase genome coverage and power for genome-wide association studies. Imputation has been successful for European ancestry populations in which very large reference panels are available. Smaller subsets of African descent populations are available in 1000 Genomes (1000G), the Consortium on Asthma among African ancestry Populations in the Americas (CAAPA) and the...
Paper Details
Title
Genotype imputation performance of three reference panels using African ancestry individuals.
Published Date
Apr 1, 2018
Journal
Volume
137
Issue
4
Pages
281 - 292
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Notes
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