Personalized medicine in colorectal cancer diagnosis and treatment: a systematic review of health economic evaluations

Due to its epidemiological relevance, several studies have been performed to assess the cost-effectiveness of diagnostic tests and treatments in colorectal cancer (CRC) patients. We reviewed economic evaluations on diagnosis of inherited CRC-syndromes and genetic tests for the detection of mutations associated with response to therapeutics. A systematic literature review was performed by searching the main literature databases for relevant...