Association of grey matter changes with stability and flexibility of prediction in akinetic-rigid Parkinson’s disease
Abstract
Parkinson’s disease (PD), which is caused by degeneration of dopaminergic neurons in the midbrain, results in a heterogeneous clinical picture including cognitive decline. Since the phasic signal of dopamine neurons is proposed to guide learning by signifying mismatches between subjects’ expectations and external events, we here investigated whether akinetic-rigid PD patients without mild cognitive impairment exhibit difficulties in dealing with...
Paper Details
Title
Association of grey matter changes with stability and flexibility of prediction in akinetic-rigid Parkinson’s disease
Published Date
Jan 27, 2018
Journal
Volume
223
Issue
5
Pages
2097 - 2111
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