Association between use of phthalate-containing medication and semen quality among men in couples referred for assisted reproduction

Does phthalate exposure from prescription drugs affect semen quality?Exposure to phthalate-containing drugs is associated with poor semen quality.Phthalates and their metabolites have been shown to disrupt the hormone signalling in animal studies. One study has shown associations between medicinal phthalate exposure and poor semen quality, suggesting similar effects in humans.We included 18 515 males with poor semen quality (cases) and 31 063...