Abstract #850: Cytotoxic activity of two pleurocidin-like cationic antimicrobial peptides against human breast cancer cells

Cationic antimicrobial peptides are small peptides that constitute an important defense against microbial pathogens and, in some cases, also exhibit potent cytotoxic activity against cancer cells. Atlantic pleuronectid flatfish are a particularly rich source of cationic antimicrobial peptides, including NRC-03 and NRC-07, which are pleurocidin-like peptides derived from winter and yellowtail flounder, respectively. The purpose of this...