Accurate analysis of genuine CRISPR editing events with ampliCan

Pages: 249474
Published: Jan 17, 2018
Abstract
We present ampliCan, an analysis tool that unites identification, quantification and visualization of genuine genome editing events from CRISPR amplicon sequencing data. ampliCan overcomes methodological challenges suffered by other tools to estimate the true mutational efficiency in a high-throughput automated fashion. ampliCan controls for biases at every step of the analysis and generates reports that allow users to quickly identify...
Paper Details
Title
Accurate analysis of genuine CRISPR editing events with ampliCan
Published Date
Jan 17, 2018
Journal
Pages
249474
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