Inhalation of peptide-loaded nanoparticles improves heart failure
Abstract
Peptides are highly selective and efficacious for the treatment of cardiovascular and other diseases. However, it is currently not possible to administer peptides for cardiac-targeting therapy via a noninvasive procedure, thus representing scientific and technological challenges. We demonstrate that inhalation of small (<50 nm in diameter) biocompatible and biodegradable calcium phosphate nanoparticles (CaPs) allows for rapid translocation of...
Paper Details
Title
Inhalation of peptide-loaded nanoparticles improves heart failure
Published Date
Jan 17, 2018
Volume
10
Issue
424
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