Immunoisolating poly(ethylene glycol) based capsules support ovarian tissue survival to restore endocrine function

Volume: 106, Issue: 5, Pages: 1381 - 1389
Published: Feb 5, 2018
Abstract
A common irreversible adverse effect of life‐saving anticancer treatments is loss of gonadal endocrine function and fertility, calling for a need to focus on post‐treatment quality of life. Here, we investigated the use of poly(ethylene glycol)‐vinyl sulfone (PEG‐VS) based capsules to support syngeneic donor ovarian tissue for restoration of endocrine function in mice. We designed a dual immunoisolating capsule (PEG‐Dual) by tuning the physical...
Paper Details
Title
Immunoisolating poly(ethylene glycol) based capsules support ovarian tissue survival to restore endocrine function
Published Date
Feb 5, 2018
Volume
106
Issue
5
Pages
1381 - 1389
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