Loss of VAMP5 in mice results in duplication of the ureter and insufficient expansion of the lung
Abstract
Vesicle-associated membrane protein 5 (VAMP5) is a member of the SNARE protein family, which regulates the docking and fusion of membrane vesicles within cells. Previously, we reported ubiquitous expression of VAMP5 proteins in various organs except the brain and small intestine. However, the precise roles of VAMP5 in each organ remain unclear. To explore the roles of VAMP5 in vivo, we generated VAMP5 knockout (KO) mice.VAMP5 KO mice showed low...
Paper Details
Title
Loss of VAMP5 in mice results in duplication of the ureter and insufficient expansion of the lung
Published Date
Feb 10, 2018
Journal
Volume
247
Issue
5
Pages
754 - 762
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