Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses
Abstract
Recent studies have identified intracellular metabolism as a fundamental determinant of macrophage function. In obesity, proinflammatory macrophages accumulate in adipose tissue and trigger chronic low-grade inflammation, that promotes the development of systemic insulin resistance, yet changes in their intracellular energy metabolism are currently unknown. We therefore set out to study metabolic signatures of adipose tissue macrophages (ATMs)...
Paper Details
Title
Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses
Published Date
Jan 14, 2018
Journal
Volume
61
Issue
4
Pages
942 - 953
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Notes
History