Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System.

Neuron16.20
Volume: 97, Issue: 2, Pages: 313
Published: Jan 17, 2018
Abstract
Summary null N 6 -methyladenosine (m 6 A) affects multiple aspects of mRNA metabolism and regulates developmental transitions by promoting mRNA decay. Little is known about the role of m 6 A in the adult mammalian nervous system. Here we report that sciatic nerve lesion elevates levels of m 6 A-tagged transcripts encoding many regeneration-associated genes and protein translation machinery components in the adult mouse dorsal root ganglion...
Paper Details
Title
Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System.
Published Date
Jan 17, 2018
Journal
Volume
97
Issue
2
Pages
313
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