Activation of AKT-mTOR Signaling Directs Tenogenesis of Mesenchymal Stem Cells
Abstract
Tendon repair is a clinical challenge because of the limited understanding on tenogenesis. The synthesis of type I collagen (Collagen I) and other extracellular matrix are essential for tendon differentiation and homeostasis. Current studies on tenogenesis focused mostly on the tenogenic transcriptional factors while the signaling controlling tenogenesis on translational level remains largely unknown. Here, we showed that mechanistic target of...
Paper Details
Title
Activation of AKT-mTOR Signaling Directs Tenogenesis of Mesenchymal Stem Cells
Published Date
Jan 5, 2018
Journal
Volume
36
Issue
4
Pages
527 - 539
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History