Match!

Erratum: From Krebs to clinic: glutamine metabolism to cancer therapy

Published on Nov 1, 2016in Nature Reviews Cancer51.848
· DOI :10.1038/nrc.2016.114
Brian J. Altman19
Estimated H-index: 19
,
Zachary E. Stine9
Estimated H-index: 9
,
Chi V. Dang84
Estimated H-index: 84
Sources
Abstract
Nature Reviews Cancer 16, 619–634 (2016) Reference 32 was incorrectly cited on page 626 and references 128, 129, 134 and 135 were incorrectly cited in Table 1. These have now been replaced with the correct references.
  • References (1)
  • Citations (41)
📖 Papers frequently viewed together
336 Citations
6,518 Citations
26.2k Citations
78% of Scinapse members use related papers. After signing in, all features are FREE.
References1
Newest
#1Brian J. AltmanH-Index: 19
#2Zachary E. StineH-Index: 9
Last. Chi V. DangH-Index: 84
view all 3 authors...
336 CitationsSource
Cited By41
Newest
#1Tahany M. Maharem (Ain Shams University)H-Index: 5
#2Manal A. Emam (Ain Shams University)H-Index: 6
Last. Youssef A. Said (Ain Shams University)
view all 3 authors...
Abstract L-Glutaminase has gained an important attention as glutamine-depleting enzyme in treatment of various cancers. Therefore, this study aimed to purify, characterize, investigate antitumor activity of L-glutaminase from camel liver mitochondria (CL-Glu), since no available information about CL-Glu from camel. CL-Glu was purified using cell fractionation, ultrafiltration, DEAE-and CM-cellulose chromatography columns. The purified CL-Glu was a monomer with a molecular weight of 70 ± 3 kDa, i...
Source
Last. He Teng (Tianjin Medical University)
view all 4 authors...
Purpose: Energy compromise underpins wet age-related macular degeneration (wAMD) pathogenesis, but the relationship between glucose metabolism and the disease remains unclear. Here, we characterized aqueous humor (AH) to elucidate glucose-related metabolic signatures in patients with wAMD. Methods: In total, 25 eyes of 25 patients with wAMD were divided into phakic (15 eyes), pseudophakic (10 eyes), and intravitreal injections of ranibizumab (13 eyes) wAMD groups. Twenty patients with cataract (...
Source
#1Emiliano Panieri (Sapienza University of Rome)H-Index: 2
#1Emiliano PanieriH-Index: 11
Last. Sibel SuzenH-Index: 21
view all 11 authors...
The nuclear factor erythroid 2-related factor 2 (NRF2)–Kelch-like ECH-associated protein 1 (KEAP1) regulatory pathway plays an essential role in protecting cells and tissues from oxidative, electrophilic, and xenobiotic stress. By controlling the transactivation of over 500 cytoprotective genes, the NRF2 transcription factor has been implicated in the physiopathology of several human diseases, including cancer. In this respect, accumulating evidence indicates that NRF2 can act as a double-edged ...
4 CitationsSource
#1Mouradi El HoutH-Index: 1
#2Emma CosiallsH-Index: 1
Last. Ahmed HamaïH-Index: 12
view all 4 authors...
Cancer is now considered as a heterogeneous ecosystem in which tumor cells collaborate with each other and with host cells in their microenvironment. As circumstances change, the ecosystem evolves to ensure the survival and growth of the cancer cells. In this ecosystem, metabolism is not only a key player but also drives stemness. In this review, we first summarize our current understanding of how autophagy influences cancer stem cell phenotype. We emphasize metabolic pathways in cancer stem cel...
3 CitationsSource
#1Lu Lu (Peking Union Medical College)H-Index: 7
#2Hang Li (Peking Union Medical College)
Last. Qiang Shen (LSU: Louisiana State University)H-Index: 15
view all 7 authors...
OBJECTIVES: Signal transducer and activator of transcription 3 (STAT3) is constitutively activated and overexpressed in many cancers, including non-small-cell lung cancer (NSCLC). We recently developed HJC0152 as an orally active STAT3 inhibitor. This study focused on investigating HJC0152's effect and mechanism of action in NSCLC. MATERIALS AND METHODS: We analysed cell proliferation by MTT assays, cell migration by wound healing and transwell assays, protein levels by Western blot, and apoptos...
Source
#1Cindy Mendes (Instituto Português de Oncologia Francisco Gentil)
#2Jacinta Serpa (Instituto Português de Oncologia Francisco Gentil)H-Index: 11
Metabolic remodelling is a hallmark of cancer, however little has been unravelled in its role in chemoresistance, which is a major hurdle to cancer control. Lung cancer is a leading cause of death by cancer, mainly due to the diagnosis at an advanced stage and to the development of resistance to therapy. Targeted therapeutic agents combined with comprehensive drugs are commonly used to treat lung cancer. However, resistance mechanisms are difficult to avoid. In this review, we will address some ...
1 CitationsSource
#1Jieying Zhang (Tongji University)H-Index: 1
#2Zhaopeng Shi (SJTU: Shanghai Jiao Tong University)H-Index: 1
Last. Jun Mi (SJTU: Shanghai Jiao Tong University)H-Index: 5
view all 5 authors...
1 CitationsSource
#1Esmeralda Ramirez-Peña (NIH: National Institutes of Health)H-Index: 1
Last. Sendurai A. ManiH-Index: 38
view all 17 authors...
Identifying bioenergetics that facilitate the epithelial to mesenchymal transition (EMT) in breast cancer cells may uncover targets to treat incurable metastatic disease. Metastasis is the number one cause of cancer-related deaths; therefore, it is urgent to identify new treatment strategies to prevent the initiation of metastasis. To characterize the bioenergetics of EMT, we compared metabolic activities and gene expression in cells induced to differentiate into the mesenchymal state with their...
2 CitationsSource
#1Isabelle MagalhaesH-Index: 11
#2Ohad Yogev (UCL: University College London)H-Index: 9
Last. Anna SchurichH-Index: 16
view all 4 authors...
Upon activation naive T cells undergo metabolic changes to support the differentiation into subsets of effector or regulatory cells, and enable subsequent metabolic adaptations to form memory. Interfering with these metabolic alterations leads to abrogation or reprogramming of T cell differentiation, demonstrating the importance of these pathways in T cell development. It has long been appreciated that the conversion of a healthy cell to a cancerous cell is accompanied by metabolic changes, whic...
Source
#1Lei Bao (PSU: Pennsylvania State University)H-Index: 37
#2Fernanda Festa (PSU: Pennsylvania State University)H-Index: 7
Last. Barbara A. Miller (PSU: Pennsylvania State University)H-Index: 34
view all 11 authors...
Transient receptor potential melastatin channel subfamily member 2 (TRPM2) has an essential role in protecting cell viability through modulation of oxidative stress. TRPM2 is highly expressed in cancer. When TRPM2 is inhibited, mitochondria are dysfunctional, ROS levels are increased, and cell viability is reduced. Here, the importance of NF-E2-related factor (Nrf2) in TRPM2-mediated suppression of oxidant stress was explored. In TRPM2 depleted cells, antioxidant cofactors glutathione, NADPH, an...
Source