RNA sequencing for early response analysis to chemotherapy in gastric cancer.

e15051 Background: Response to chemotherapy is a prognostic factor for patients with gastric cancer (GaCa). No biomarkers exist to predict response to chemotherapy despite a number of expression studies on the subject. We analyzed early response to chemotherapy by sequential RNA sequencing, pre- and post-therapy as a proof of principle study. Methods: Ten patients with local advanced GaCa were included.Tumor and benign tissues were...