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C-Reactive Protein on Postoperative Day 1 Is a Reliable Predictor of Pancreas-Specific Complications After Pancreaticoduodenectomy

Published on May 1, 2018in Journal of Gastrointestinal Surgery2.69
· DOI :10.1007/s11605-017-3658-9
Théophile Guilbaud2
Estimated H-index: 2
(AMU: Aix-Marseille University),
David Jérémie Birnbaum6
Estimated H-index: 6
(AMU: Aix-Marseille University)
+ 5 AuthorsVincent Moutardier29
Estimated H-index: 29
(AMU: Aix-Marseille University)
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Abstract
Background Postoperative pancreatic fistula and pancreas-specific complications have a significant influence on patient management and outcomes after pancreatoduodenectomy. The aim of the study was to assess the value of serum C-reactive protein on the postoperative day 1 as early predictor of pancreatic fistula and pancreas-specific complications.
  • References (60)
  • Citations (1)
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References60
Newest
Published on Jun 1, 2017in Annals of Surgery9.48
Matthew T. McMillan15
Estimated H-index: 15
,
Giuseppe Malleo28
Estimated H-index: 28
+ 10 AuthorsAlessandra Pulvirenti6
Estimated H-index: 6
Objective:This multicenter study sought to prospectively evaluate a drain management protocol for pancreatoduodenectomy (PD).Background:Recent evidence suggests value for both selective drain placement and early drain removal for PD. Both strategies have been associated with reduced rates of clinica
Published on Mar 1, 2017in Surgery3.48
Claudio Bassi79
Estimated H-index: 79
,
Giovanni Marchegiani17
Estimated H-index: 17
+ 30 AuthorsMarc G. Besselink33
Estimated H-index: 33
(UvA: University of Amsterdam)
Background: In 2005, the International Study Group of Pancreatic Fistula developed a definition and grading of postoperative pancreatic fistula that has been accepted universally. Eleven years later, because postoperative pancreatic fistula remains one of the most relevant and harmful complications of pancreatic operation, the International Study Group of Pancreatic Fistula classification has become the gold standard in defining postoperative pancreatic fistula in clinical practice. The aim of t...
Published on Aug 1, 2016in Journal of Gastrointestinal Surgery2.69
Alessandro Giardino7
Estimated H-index: 7
,
Gaya Spolverato28
Estimated H-index: 28
+ 7 AuthorsGiovanni Butturini35
Estimated H-index: 35
Background The association between postoperative inflammatory markers and risk of complications after pancreaticoduodenectomy (PD) is controversial. We sought to assess the diagnostic value of perioperative C-reactive protein (CRP) and procalcitonin (PCT) levels in the early identification of patients at risk for complications after PD.
Published on Apr 1, 2016in British Journal of Surgery5.59
L.K. Palani Velu1
Estimated H-index: 1
(Glasgow Royal Infirmary),
C. J. McKay12
Estimated H-index: 12
(Glasgow Royal Infirmary)
+ 3 AuthorsEuan J. Dickson14
Estimated H-index: 14
(Glasgow Royal Infirmary)
Background Pancreas-specific complications (PSCs), comprising postoperative pancreatic fistula, haemorrhage and intra-abdominal collections, are drivers of morbidity and mortality after pancreaticoduodenectomy (PD). A serum amylase concentration of 130 units/l or more on postoperative day (POD) 0 has been shown to be an objective surrogate of pancreatic texture, a determinant of PSCs. This study evaluated serial measurements of C-reactive protein (CRP) to refine PSC risk stratification. Methods ...
Published on Feb 1, 2016in Medicine1.87
Xiongxiong Lu7
Estimated H-index: 7
,
Xinjing Wang6
Estimated H-index: 6
+ 5 AuthorsBaiyong Shen18
Estimated H-index: 18
Early detection of postoperative pancreatic fistula (POPF) may help to improve the outcome following pancreatic surgery, and exclusion of POPF may allow early drain removal which can accelerate recovery. The aim of this study was to evaluate the diagnostic accuracy of drain/plasma pancreatic amylase values on postoperative day 1 (DPA1/PPA1) in POPF by means of a systemic review and meta-analysis. Online journal databases and a manual search up to March 2015 were used. Studies clearly documenting...
Published on Oct 1, 2015in International Journal of Surgery
Ji Yang2
Estimated H-index: 2
(Anhui Medical University),
Qiang Huang2
Estimated H-index: 2
(Anhui Medical University),
Chao Wang2
Estimated H-index: 2
(Anhui Medical University)
Abstract Background and objectives This study to evaluate the utility of drain fluid amylase as a predictor of PF in patients undergoing pancreatic surgery based on the International Study Group of Pancreatic Fistula definitions of pancreatic fistula. Methods A comprehensive search was carried out using Pubmed (Medline), Embase, Web of science and Cochrane database for clinical trials, which studied DFA as a diagnostic marker for pancreatic fistula after pancreatic surgery. Sensitivity, specific...
Published on Sep 1, 2015in International Journal of Surgery
Raffaele Dalla Valle7
Estimated H-index: 7
,
Mario De Bellis1
Estimated H-index: 1
+ 4 AuthorsMaurizio Iaria4
Estimated H-index: 4
Abstract Introduction Postoperative pancreatic fistula (POPF) is the most significant cause of morbidity and mortality after pancreaticoduodenectomy (PD). We evaluated the role of postoperative serum lipase concentration in ruling out POPF in the immediate post-operative period. Materials and methods We retrospectively analysed 98 consecutive PD performed between January 2009 and December 2014, investigating the correlation between postoperative day 1 (POD1) serum lipase concentration and POPF d...
Published on Aug 1, 2015in British Journal of Surgery5.59
Caroline Williamsson4
Estimated H-index: 4
(Lund University),
N Karlsson1
Estimated H-index: 1
(Lund University)
+ 3 AuthorsBobby Tingstedt18
Estimated H-index: 18
(Lund University)
Fast-track (FT) programmes are multimodal, evidence-based approaches to optimize patient outcome after surgery. The aim of this study was to evaluate the safety, clinical outcome and patients' experience of a FT programme after pancreaticoduodenectomy (PD) in a high-volume institution in Sweden.
Published on Aug 1, 2015in Journal of The American College of Surgeons4.45
Alain Sauvanet73
Estimated H-index: 73
,
Jean-Marie Boher2
Estimated H-index: 2
(IRD: Institut de recherche pour le développement)
+ 7 AuthorsJean-Robert Delpero23
Estimated H-index: 23
Background The influence of jaundice on outcomes after pancreaticoduodenectomy (PD) for pancreatic ductal adenocarcinoma (PDAC) is debated. This study aimed to determine, in a large multicentric series, the influence of severe jaundice (serum bilirubin level ≥250 μmol/L and 300 μmol/L) on early severe morbidity and survival after PD. Study Design From 2004 to 2009, twelve hundred patients (median age 66 years, 57% male) with resectable PDAC underwent PD. Patients who received preoperative biliar...
Published on Jan 1, 2015in Hpb3.05
Daniel J. Kagedan6
Estimated H-index: 6
,
Mahrosh Ahmed1
Estimated H-index: 1
(Princess Margaret Cancer Centre)
+ 1 AuthorsAlice C. Wei17
Estimated H-index: 17
(U of T: University of Toronto)
Background Enhanced recovery after surgery (ERAS) protocols have been shown to reduce hospital stay without compromising outcomes. Attempts to apply ERAS principles in the context of pancreatic surgery have generated encouraging results. A systematic review of the current evidence for ERAS following pancreatic surgery was conducted.