The efficacy and safety of mannitol challenge in a workplace setting for assessing asthma prevalence

There is no standard definition of asthma for epidemiological purposes; most surveys use symptoms and bronchial hyperresponsiveness. Few studies tested mannitol challenge test (MCT) in occupational settings. We sought to determine efficacy and safety of MCT in detecting subjects with asthma symptoms in the workplace.In this cross-sectional study we recruited 908 workers in 2 universities; they underwent a respiratory questionnaire, spirometry,...