Original paper
Multi-trait analysis of genome-wide association summary statistics using MTAG
Abstract
We introduce multi-trait analysis of GWAS (MTAG), a method for joint analysis of summary statistics from genome-wide association studies (GWAS) of different traits, possibly from overlapping samples. We apply MTAG to summary statistics for depressive symptoms (Neff = 354,862), neuroticism (N = 168,105), and subjective well-being (N = 388,538). As compared to the 32, 9, and 13 genome-wide significant loci identified in the single-trait GWAS (most...
Paper Details
Title
Multi-trait analysis of genome-wide association summary statistics using MTAG
Published Date
Jan 1, 2018
Journal
Volume
50
Issue
2
Pages
229 - 237
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Notes
History