Phenomenology and disease progression of chorea-acanthocytosis patients in Spain

•Feeding dystonia, trunk spasms, head-drops and orolingual mutilations are distinctive features of ChAc. •Severe dysarthria and dysphagia were considered the most limiting aspects of ChAc during early stages of the disease. •Hyperkinetic movements give way to parkinsonism during follow up. •Ten years after diagnosis only 50% of patients retain self-care...