Trends in oral and vaginally administered estrogen use among US women 50 years of age or older with commercial health insurance

Objective: We aimed to provide information through 2015 about use in the United States of estrogen products, including orally and vaginally administered products, in postmenopausal women. Methods: We used prescription claims for US commercial health insurance to calculate, in women 50 years of age or older ( n = 12,007,364), the age-standardized and age-specific annual prevalence of estrogen use, by formulation and route of administration, for...