Psychiatric polygenic risk associates with cortical morphology and functional organization in aging
Abstract
Common brain abnormalities in cortical morphology and functional organization are observed in psychiatric disorders and aging, reflecting shared genetic influences. This preliminary study aimed to examine the contribution of a polygenetic risk for psychiatric disorders (PRScross) to aging brain and to identify molecular mechanisms through the use of multimodal brain images, genotypes, and transcriptome data. We showed age-related cortical...
Paper Details
Title
Psychiatric polygenic risk associates with cortical morphology and functional organization in aging
Published Date
Dec 11, 2017
Journal
Volume
7
Issue
12
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