Synthesis and evaluation of the antibiotic and adjuvant antibiotic potential of organotin(IV) derivatives
Abstract
A series of organotin(IV) derivatives was investigated in vitro for their antibiotic and adjuvant antibiotic properties (efflux pump inhibitors) against Staphylococcus aureus strains that overexpress efflux pump proteins for norfloxacin (SA-1199B), erythromycin (RN-4220) and tetracycline (IS-58). Most organotin(IV) compounds showed significant antibacterial activity with small Minimum Inhibitory Concentration (MIC) values, some of which were...
Paper Details
Title
Synthesis and evaluation of the antibiotic and adjuvant antibiotic potential of organotin(IV) derivatives
Published Date
Mar 1, 2018
Volume
180
Pages
80 - 88
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