Original paper
A new mitofusin topology places the redox-regulated C terminus in the mitochondrial intermembrane space
Abstract
Mitochondrial fusion occurs in many eukaryotes, including animals, plants, and fungi. It is essential for cellular homeostasis, and yet the underlying mechanisms remain elusive. Comparative analyses and phylogenetic reconstructions revealed that fungal Fzo1 and animal Mitofusin proteins are highly diverged from one another and lack strong sequence similarity. Bioinformatic analysis showed that fungal Fzo1 proteins exhibit two predicted...
Paper Details
Title
A new mitofusin topology places the redox-regulated C terminus in the mitochondrial intermembrane space
Published Date
Dec 6, 2017
Journal
Volume
217
Issue
2
Pages
507 - 515
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Notes
History