A phase III randomized trial of gantenerumab in prodromal Alzheimer’s disease
Abstract
Gantenerumab is a fully human monoclonal antibody that binds aggregated amyloid-β (Aβ) and removes Aβ plaques by Fc receptor-mediated phagocytosis. In the SCarlet RoAD trial, we assessed the efficacy and safety of gantenerumab in prodromal Alzheimer’s disease (AD). In this randomized, double-blind, placebo-controlled phase III study, we investigated gantenerumab over 2 years. Patients were randomized to gantenerumab 105 mg or 225 mg or placebo...
Paper Details
Title
A phase III randomized trial of gantenerumab in prodromal Alzheimer’s disease
Published Date
Dec 1, 2017
Volume
9
Issue
1
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