Influence of the intestinal microbiota on the immunogenicity of oral rotavirus vaccine given to infants in south India.

Volume: 36, Issue: 2, Pages: 264 - 272
Published: Jan 4, 2018
Abstract
Oral rotavirus vaccines have consistently proven to be less immunogenic among infants in developing countries. Discrepancies in the intestinal microbiota, including a greater burden of enteropathogens and an altered commensal community composition, may contribute to this trend by inhibiting the replication of vaccine viruses. To test this possibility, we performed a nested case-control study in Vellore, India, in which we compared the intestinal...
Paper Details
Title
Influence of the intestinal microbiota on the immunogenicity of oral rotavirus vaccine given to infants in south India.
Published Date
Jan 4, 2018
Journal
Volume
36
Issue
2
Pages
264 - 272
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