Iridium/Chiral Diene‐Catalyzed Enantioselective (3+2) Annulation of Aromatic Ketimines with 1,3‐Enynes via C−H Activation

An iridium/chiral diene complex efficiently catalyzed enantioselective (3+2) annulation between 1,3‐enynes and cyclic N ‐acyl ketimines generated in situ from 3‐aryl‐3‐hydroxyisoindoin‐1‐ones. The reaction gave the corresponding aminoindane derivatives in high yields with high regio‐, diastereo‐, and enantioselectivity. magnified...