Original paper

Iridium/Chiral Diene‐Catalyzed Enantioselective (3+2) Annulation of Aromatic Ketimines with 1,3‐Enynes via C−H Activation

Volume: 360, Issue: 4, Pages: 791 - 795
Published: Jan 4, 2018
Abstract
An iridium/chiral diene complex efficiently catalyzed enantioselective (3+2) annulation between 1,3‐enynes and cyclic N ‐acyl ketimines generated in situ from 3‐aryl‐3‐hydroxyisoindoin‐1‐ones. The reaction gave the corresponding aminoindane derivatives in high yields with high regio‐, diastereo‐, and enantioselectivity. magnified...
Paper Details
Title
Iridium/Chiral Diene‐Catalyzed Enantioselective (3+2) Annulation of Aromatic Ketimines with 1,3‐Enynes via C−H Activation
Published Date
Jan 4, 2018
Volume
360
Issue
4
Pages
791 - 795
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