Antisense oligonucleotides: the next frontier for treatment of neurological disorders
Abstract
Two decades after antisense oligonucleotides (ASOs) were initially identified as agents capable of modulating RNA processing and protein expression, the first antisense oligonucleotide (ASO) therapies have now been approved for the treatment of neurological disease. Here, Rinaldi and Wood discuss our current understanding of ASO pharmacology, and the future prospects for ASO-mediated treatment of neurological disease Antisense oligonucleotides...
Paper Details
Title
Antisense oligonucleotides: the next frontier for treatment of neurological disorders
Published Date
Dec 1, 2017
Journal
Volume
14
Issue
1
Pages
9 - 21
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