Genetic Association of Lipids and Lipid Drug Targets With Abdominal Aortic Aneurysm

Risk factors for abdominal aortic aneurysm (AAA) are largely unknown, which has hampered the development of nonsurgical treatments to alter the natural history of disease.To investigate the association between lipid-associated single-nucleotide polymorphisms (SNPs) and AAA risk.Genetic risk scores, composed of lipid trait-associated SNPs, were constructed and tested for their association with AAA using conventional (inverse-variance weighted)...