Hyaluronan and Hyaluronan Fragments
Abstract
The glycosaminoglycan hyaluronan (HA) is a key component of the microenvironment surrounding cells. In healthy tissues, HA molecules have extremely high molecular mass and consequently large hydrodynamic volumes. Tethered to the cell surface by clustered receptor proteins, HA molecules crowd each other, as well as other macromolecular species. This leads to severe nonideality in physical properties of the biomatrix, because steric exclusion...
Paper Details
Title
Hyaluronan and Hyaluronan Fragments
Published Date
Jan 1, 2017
Volume
74
Pages
1 - 59
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