Effects of hawthorn ( Crataegus pentagyna ) leaf extract on electrophysiologic properties of cardiomyocytes derived from human cardiac arrhythmia‐specific induced pluripotent stem cells

Cardiac arrhythmias are major life-threatening conditions. The landmark discovery of induced pluripotent stem cells has provided a promising in vitro system for modeling hereditary cardiac arrhythmias as well as drug development and toxicity testing. Nowadays, nutraceuticals are frequently used as supplements for cardiovascular therapy. Here we studied the cardiac effects of hawthorn ( Crataegus pentagyna) leaf extract using cardiomyocytes (CMs)...