Genome-wide meta-analysis identifies novel determinants of circulating serum progranulin
Abstract
Progranulin is a secreted protein with important functions in processes including immune and inflammatory response, metabolism and embryonic development. The present study aimed at identification of genetic factors determining progranulin concentrations. We conducted a genome-wide association meta-analysis for serum progranulin in three independent cohorts from Europe: Sorbs (N = 848) and KORA (N = 1628) from Germany and PPP-Botnia (N = 335)...
Paper Details
Title
Genome-wide meta-analysis identifies novel determinants of circulating serum progranulin
Published Date
Nov 27, 2017
Journal
Volume
27
Issue
3
Pages
546 - 558
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