Redox Regulation Of Kinases In The Heart

Volume: 112, Pages: 2
Published: Nov 1, 2017
Abstract
Oxidants can induce intra-and interdisulfide formation in protein kinases. This has been reported to regulate kinase activity by altering their cellular compartmentalization, relieving an inhibitory structure or by mimicking second messenger binding. For protein kinases as cAMP- and cGMP-dependent protein kinase, structural evidence confirmed indeed the presence of such disulfide modifications. Studies performed in redox-dead mice that can no...
Paper Details
Title
Redox Regulation Of Kinases In The Heart
Published Date
Nov 1, 2017
Volume
112
Pages
2
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