Motor fatigability in persons with multiple sclerosis: Relation between different upper limb muscles, and with fatigue and the perceived use of the arm in daily life

Background Motor fatigability is increasingly acknowledged in persons with MS (pwMS). It is unknown whether fatigability is generalized across upper limb muscles and relates to fatigue and perceived difficulties in upper limb use. Methods This observational case-controlled study included twenty PwMS (median EDSS = 3, range 1.5–6.5) and twenty healthy controls who performed 30″ sustained maximal muscle contractions for index finger abduction,...