Original paper

Lambda phage nanoparticles displaying HER2-derived E75 peptide induce effective E75-CD8+ T response

Volume: 66, Issue: 1, Pages: 200 - 206
Published: Nov 16, 2017
Abstract
We have investigated the in vitro immunogenicity and in vivo prophylactic and therapeutic potential of lambda (λ) phage particles displaying the E75 peptide (derived from HER2 protein) in an implantable TUBO breast tumor model of BALB/c mice. The mice were immunized with the E75-displaying phage (λF7-gpD::E75) every 2-week intervals over a 6-week period, and the generated immune responses were studied. Results showed in vitro induction of immune...
Paper Details
Title
Lambda phage nanoparticles displaying HER2-derived E75 peptide induce effective E75-CD8+ T response
Published Date
Nov 16, 2017
Volume
66
Issue
1
Pages
200 - 206
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