Human abuse potential of brivaracetam in healthy recreational central nervous system depressant users

Background Brivaracetam is a new antiepileptic drug indicated for adjunctive treatment of focal seizures in adults at a dose of 50–200 mg/day taken in two equal doses. The objective of this study was to evaluate the abuse potential of brivaracetam compared with alprazolam (positive control), placebo, and levetiracetam. Methods This was a randomized, double-blind, triple-dummy, crossover study in healthy male and female recreational central...