Mutual interactions between telomere heterogeneity and cell culture growth dynamics shape stochasticity of cell aging

Volume: 19, Issue: 1, Pages: 23 - 31
Published: Feb 1, 2018
Abstract
Mathematical modeling and computational simulations are often used to explain the stochastic nature of cell aging. The models published thus far are based on the molecular mechanisms of telomere biology and how they dictate the dynamics of cell culture proliferation. However, the influence of cell growth conditions on telomere dynamics has been widely overlooked. These conditions include interactions with surrounding cells through contact...
Paper Details
Title
Mutual interactions between telomere heterogeneity and cell culture growth dynamics shape stochasticity of cell aging
Published Date
Feb 1, 2018
Volume
19
Issue
1
Pages
23 - 31
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