P4 Isolated mediastinal lymph node tuberculosis (imlntb) is characterised by elevation in systemic and bronchial il-12 pathway mediators compared to pulmonary tb

Introduction/Aims

The incidence of isolated mediastinal lymph node tuberculosis (IMLNTB) has increased in recent years in the UK. These patients exhibit a distinct clinical phenotype compared to patients with pulmonary TB (PTB), more likely to be asymptomatic or presenting with immune hypersensitivity. The mediastinal lymph nodes are of particular interest in TB as they have been implicated as a key site for host-pathogen interaction,...