Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer
Abstract
Colorectal cancers comprise a complex mixture of malignant cells, nontransformed cells, and microorganisms. Fusobacterium nucleatum is among the most prevalent bacterial species in colorectal cancer tissues. Here we show that colonization of human colorectal cancers with Fusobacterium and its associated microbiome-including Bacteroides, Selenomonas, and Prevotella species-is maintained in distal metastases, demonstrating microbiome stability...
Paper Details
Title
Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer
Published Date
Dec 15, 2017
Journal
Volume
358
Issue
6369
Pages
1443 - 1448
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